Fluorescent Products

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Fluorescent pyrrole products from carbonyl-amine reactions.

The reaction of (E)-4,5-epoxy-(E)-2-heptenal with butylamine and glycine methyl ester produced brown macromolecular pigments, which showed fluorescent characteristics similar to lipofuscins. This polymerization reaction implies in the first step the formation of 1-alkyl-2-(1'-hydroxyalkyl)pyrroles (IV, VI). Compounds IV and VI have been isolated and characterized from the above reactions, and t...

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Fluorescent lipid-peroxidation products in synovial fluid.

1. Samples and extracts from synovial effusions were examined for the presence of fluorescent degradation products of free-radical oxidation (peroxidation). 2. Two classes of fluorescent compounds were identified and their fluorescence and physical properties are described. The fluorescence in the aqueous methanol phase of the extracts had the characteristics of conjugated Schiff bases. 3. Chan...

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PREPARATION AND APPLICATIONS OF FLUORESCENT POLYGLUTARALDEHYDE IMMUNOMICROSPHERES

Aqueous glutaraldehyde has been polymerized under alkaline conditions in the presence of a surfactant to yield microspheres of varied diameters. Microbeads of a nominal 300 nm diameter, made fluorescent via fluoresceinisothiocyanate, were used as a carrier of rabbit anti-human red blood cell antibodies. Specific labeling of the human red blood cells as well as diagnostic use of these fluor...

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Fluorescent molecular peroxidation products: a prognostic biomarker of early neurologic deterioration after thrombolysis.

BACKGROUND AND PURPOSE Fluorescent molecular peroxidation products (FMPPs) are considered potential markers of molecular oxidative damage and may provoke increased permeability and disruption of the blood-brain barrier. This study aimed to determine the value of FMPPs as a biomarker to predict neurological worsening related to early hemorrhagic transformation. METHODS Baseline FMPP levels wer...

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Original Contribution Plasma Fluorescent Oxidation Products: Independent Predictors of Coronary Heart Disease in Men

Fluorescent oxidation products in plasma are stable with routine blood collection methods and reflect oxidation in food, animals, and in vitro. Whether plasma fluorescent oxidation products predict future coronary heart disease has not been established. Among US men without cardiovascular disease who provided blood specimens in 1994 in the Health Professionals Follow-up Study, the authors confi...

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ژورنال

عنوان ژورنال: Pharmaceutica Analytica Acta

سال: 2013

ISSN: 2153-2435

DOI: 10.4172/2153-2435.1000e152